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Genome editing reduces cholesterol in large animal model, laying human trial groundwork

by Staff July 9, 2018
July 9, 2018 57 views
57

Using genome editing to inactivate a protein called PCSK9 effectively reduced cholesterol levels in rhesus macaques. This is the first demonstration of a clinically relevant reduction of gene expression in a large animal model using genome editing. The study describes a possible new approach for treating heart disease patients who do not tolerate PCSK9 inhibitors — drugs that are commonly used to combat high cholesterol.

Source: sciencedaily.com

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