When experts compare the DNA left at a crime scene with the DNA of a suspect, they generate statistics that describe how closely those DNA samples match. These match statistics are reliable because they’re based on rigorous scientific research. However, that research only applies to DNA fingerprints, also called DNA profiles, that have been generated using current technology. Now, scientists have laid the statistical foundation for calculating match statistics when using Next Generation Sequencing, or NGS, which produces DNA profiles that can be more useful in solving some crimes.
NIST builds statistical foundation for next-generation forensic DNA profiling