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Lysosomes are organelles that play essential roles in cellular digestion and waste management, and lysosomal dysfunction typically leads to serious diseases. In a recent study, scientists developed a novel technique to extract intact lysosomes from cells using magnetic nanoparticles. Their approach is much faster than previous methods and yields samples with high purity, allowing for a better understanding of lysosomes and their metabolites and, hopefully, paving the way to treatments for lysosomal disorders.