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Crystal structure reveals how curcumin impairs cancer

by Staff July 9, 2018
July 9, 2018 116 views

Through x-ray crystallography and kinase-inhibitor specificity profiling, researchers reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 (DYRK2) at the atomic level. This previously unreported biochemical interaction of curcumin leads to inhibition of DYRK2 that impairs cell proliferation and reduces cancer burden.

Source: sciencedaily.com

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