Feeding method and affectionate touch patterns in depressed and non-depressed mothers and babies as well as infant’s EEG activity showed that mother-infant affectionate touch differed as a function of mood and feeding method (breastfeeding and bottle-feeding). Infants in the depressed and bottle-fed group reduced touch toward their mothers while breastfeeding had a positive effect on both mother and baby. Infants of depressed and breastfeeding mothers showed neither behavioral nor brain development dysregulation previously found in infants of depressed mothers.