Researchers examine some of thelatest advances in wearable electronic devices and systems being developed using electrospinning — the fabrication of nanofibers with tunable properties from a polymer base — and showcase the many advantages electrospun materials have over conventional bulk materials. Their high surface-to-volume ratio endows them with enhanced porosity and breathability, which is important for long-term wearability, and with the appropriate blend of polymers, they can achieve superior biocompatibility.