High-resolution microscopy techniques, for example electron microscopy or super-resolution microscopy, produce huge amounts of data. The visualization, analysis and dissemination of such large imaging data sets poses significant challenges. Now, these tasks can be carried out using MoBIE, which stands for Multimodal Big Image Data Exploration, a new user-friendly, freely available tool. This means that researchers such as biologists, who rely on high-resolution microscopy techniques, can incorporate multiple data sets to study the processes of life at the very smallest scales.